Global Nexa Initiative launched to accelerate climate and health innovations in developing countries

Date: 2026-06-22
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By:   Nana Appiah Acquaye

Grand Challenges Canada (GCC) and the Science for Africa Foundation (SFA Foundation) have launched Nexa, a new global initiative aimed at supporting locally led innovations that address the growing health impacts of climate change in low- and middle-income countries.

The initiative was unveiled during London Climate Action Week in the United Kingdom and brings together a coalition of international partners seeking to strengthen health systems and improve resilience in communities most vulnerable to climate-related health risks.

Nexa is led by Grand Challenges Canada, in partnership with the Government of Canada and the Science for Africa Foundation, alongside a global network of collaborators that includes the Novo Nordisk Foundation, Sanofi Foundation, the Fund for Innovation in Development, and members of the Global Grand Challenges Network in Botswana, Brazil, Malawi, Rwanda, Senegal, and South Africa.

The initiative aims to mobilise more than US$50 million in partner investments to scale climate-health innovations. Its first funding call opened on June 22, 2026, targeting innovators across Africa and the Americas.

The launch comes amid growing concern over the health consequences of climate change. According to global health experts, rising temperatures, changing disease patterns and increasingly frequent extreme weather events are placing additional pressure on already strained healthcare systems, particularly in developing countries.

Speaking at the launch, Grand Challenges Canada Chief Executive Officer Dr. Karlee Silver said communities around the world are facing rapidly increasing threats to their health and livelihoods while global climate commitments continue to weaken. She noted that Nexa seeks to support bold, locally driven innovations that can help people remain healthy in the face of climate change.

The initiative is informed by findings from what organisers describe as the largest climate and health survey conducted to date. The survey engaged 6,400 respondents across 107 low- and middle-income countries and gathered perspectives from health workers, scientists, innovators, policymakers and humanitarian practitioners affected by climate-related health challenges.

Science for Africa Foundation Chief Executive Officer Dr. Tom Kariuki said climate and health represent one of the defining challenges of the modern era and require new approaches to partnership and investment. He emphasised that communities closest to these challenges are often best positioned to develop effective solutions.

Nexa will focus on supporting innovations that address three major climate-related health threats: changing vector-borne disease patterns, including malaria and dengue fever; extreme heat; and poor air quality. These risks disproportionately affect vulnerable populations such as children, pregnant women, individuals with chronic illnesses and underserved communities with limited access to healthcare.

The Government of Canada has expressed support for the initiative, describing investments in locally led climate and health innovations as critical to helping vulnerable communities adapt to the health impacts of climate change while strengthening global health security.

Through its funding programme, Nexa will provide support for both early-stage and growth-stage innovations. Proof-of-concept projects will be eligible for grants of up to US$200,000 over 18 to 24 months, while more mature solutions will be able to access Transition to Scale funding ranging from approximately US$250,000 to US$2 million, depending on their stage of development.

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